For optimal effectiveness, Sildigra Super Power 160 Mg (combination of Sildenafil 120 mg and Dapoxetine 40 mg) should generally be taken approximately 30 to 60 minutes before sexual activity. Key Points: Onset of Action: Sildenafil typically starts working within 30 to 60 minutes. Dapoxetine, which is used to treat premature ejaculation, may take a bit longer, around 1 to 2 hours for its full effect. Duration: The effects of Sildigra Super Power 160mg can last for 4 to 6 hours. Considerations: Empty Stomach: For the best results, taking the medication on an empty stomach or after a light meal is recommended, as fatty foods can delay absorption. Alcohol and Fatty Foods: Limit alcohol consumption and fatty meals close to the time of use for optimal effectiveness. Medical Guidance: Always consult a healthcare provider to ensure the correct dosage and timing are suitable for your specific health needs. Taking Sildigra Super Power 160 Mg around 30 to 60 minutes before planned sexual activity ensures the best results for treating erectile dysfunction and premature ejaculation.