P Force Fort 150 Mg, also known as sildenafil, works by inhibiting the enzyme PDE5 (phosphodiesterase type 5). This enzyme is primarily found in the smooth muscle cells of the penis and pulmonary vasculature. When a man is sexually stimulated, nitric oxide (NO) is released in the erectile tissue of the penis. Nitric oxide then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP). P Force Fort 150 Mg is responsible for relaxing the smooth muscles of the penile arteries, allowing blood to flow into the erectile tissue and produce an erection. PDE5 normally breaks down cGMP, which terminates the erection. By inhibiting PDE5, sildenafil prolongs the effects of cGMP, leading to sustained relaxation of the smooth muscles and increased blood flow into the penis, thereby facilitating and maintaining an erection. This mechanism of action makes P Force Fort 150 Mg an effective treatment for erectile dysfunction (ED) by enhancing the natural process of achieving and maintaining an erection when sexually stimulated.
