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What is Opana ER? OPANA ER (oxymorphone hydrochloride extended-release)is a prescription pain medication used to manage moderate to severe pain that is expected to last for an extended period of time. It is an opioid pain medication, which means it works by changing the way the brain and nervous system perceive pain. It is important to use this medication only as directed and to never take more than prescribed.  Buy Opana ER 10 mg Online How does it work?OPANA ER works by binding to specific receptors in the brain and ner... more